Anti-tumor properties of blackseed (Nigella sativa L.) extracts

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Anti-tumor properties of blackseed (Nigella sativa L.) extracts.

The objective of the present study was to evaluate the in vitro and in vivo anti-cancer effect of Nigella sativa L. seed extracts. The essential oil (IC50 = 0.6%, v/v) and ethyl acetate (IC50 = 0.75%) extracts were more cytotoxic against the P815 cell line than the butanol extract (IC50 = 2%). Similar results were obtained with the Vero cell line. Although all extracts had a comparable cytotoxi...

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Antibacterial Activity of Nigella sativa L. Seed Extracts

Most of the bacterial pathogens are resistant to existing synthetic antibacterial agents demanding an increasing effort to seek effective phytochemicals as antibacterial agents against such pathogens. Nigella sativa L. (black cumin) seeds play an important role in folk medicine and some of its major constituents are reported to be pharmacologically active. In this present work, black cumin seed...

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Anti-cancer Activity of Nigella Sativa

An extract of Smilax china, Hemidesmus indicus and Nigella Sativa on the ratio 3:2:1, prepared by boiling in water and concentrated could completely cure cases of oral canger diagnosed by modern methods. Cytotoxic studies with the three components showed activity in Nigella sativa at a concentration of 25 microgram equivalent of the dry powder against Dalton's lymphoma ascites cells. Animal exp...

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Cardio-protective and anti-cancer therapeutic potential of Nigella sativa

Nigella sativa is the miraculous plant having a lot of nutritional and medicinal benefits, and attracts large number of nutrition and pharmacological researchers. N. sativa seed composition shows that it is the blessing of nature and it contains and many bioactive compounds like thymoquinone, α-hederin, alkaloids, flavonoids, antioxidants, fatty acids many other compounds that have positive eff...

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Chemical Composition and Antioxidant Properties of the Essential Oil of Nigella Sativa L

The chemical composition of the essential oil obtained from N. sativa was analyzed by GC/MS and the components identified were: p-cymene (22.05%) followed by α-thujene (6%), α-pinene (1.11%), camphene (11%), sabinene (1%), β-pinene (7%), β-myrcene (0.21%), α-phellandrene (0.45%), limonene (0.13), γ-terpinene (5.12%), terpinolene (0.23%), camphor (1%), carvone (0.32%), thymoquinone (20.32%), thy...

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ژورنال

عنوان ژورنال: Brazilian Journal of Medical and Biological Research

سال: 2007

ISSN: 1414-431X,0100-879X

DOI: 10.1590/s0100-879x2006005000108